Prevalence and antimicrobial susceptibility of high-level gentamicin resistant enterococci isolated from urine at a hospital in Pune, India

Introduction: Enterococci are one of the common organisms isolated from hospitalized patients with urinary tract infections. Guidelines recommend testing enterococcifor susceptibility to high-level gentamicin (HLG) and streptomycin. The present study was planned determine uropathogenic enterococci in a tertiary care hospital. Materials Methods: Prospective observational research carried out at hospital for two years on all urine specimens. Identification antibiotic were performed as per standard methods. All tested high level ((120µg) resistance other recommended antimicrobial agents by Results: A total 320 susceptibility. majority elderly (34.06%) admitted (69.06%). 68.4% HLG resistant. resistant highly erythromycin (96.3%), ciprofloxacin (96.8%) nalidixic acid (97.7%). sensitive significantly (p <0.05) less except acid. Only 20.5% vancomycin. susceptible linezolid. Conclusion: demonstrated prevalence causing UTI our setting. Compared enterococci, more tested. findings highlight need mandatory effective antimicrobials treatment. IMC J Med Sci. 2023; 17(2):008. DOI: https://doi.org/10.55010/imcjms.17.018 *Correspondence: Dr. Sahjid Mukhida, Department Microbiology, D. Y. Patil Medical College, Hospital Research Centre, Vidyapeeth, Pimpri, Pune, Maharashtra, India. E-mail: [email protected]